Deerhold Japan's Genomics department provides a set of specialized services including the curation and analysis of sequence variants and the validation of clinico-genetic content of genomics software. Since 2006, our Genomics team -- comprised of experts in human genetics, genomics and bioinformatics -- has delivered high-quality analysis and research reports to support a variety of clients in a variety of clinical settings. The team’s educational backgrounds in Life Sciences and Biotechnology, high levels of proficiency in sequencing technologies and strict adherence to privacy standards, underscore Deerhold Japan’s commitment to quality. Other key advantages for clients include rapid turn-around time and cost efficiencies.
Deerhold Japan supports any type of genetic diagnostic or research center engaged in DNA sequencing, analysis of genetic changes to determine impact on disease, or providing software solutions for genomics data. Clients include commercial DNA testing laboratories and organizations engaged in research, personalized gene therapy or pharmacology. Typical users are lab directors, clinicians, scientists, genetic counselors or anyone building a personal genetic database. Genomics clients take advantage of efficiencies with respect to both time and cost.
DNA sequencing services involve analyzing sequence data of genes. Deliverables:
Variant science work includes building online databases for variants, determining the clinical significance of variants, and the validation of clinical content of genomics software. Variants are annotated according to the Human Genome Variation Society (HGVS). The curation of variants includes following process:
In addition, with our expertise and collaboration with computer engineers, we are perfectly placed to build variant databases.
Determining clinically significant variants: this determination is based on in-house or client-specific standard operating procedures, and/or the procedures outlined by the American College of Medical Genetics and Genomics (ACMG). This process includes:
In addition, with our expertise and collaboration with computer engineers, we are perfectly placed to build variant databases.
Big data in genomics has caused a tremendous growth in the development of software solutions that relate genome data to clinical and research utilities. This process includes:
In addition, with our expertise and collaboration with computer engineers, we are perfectly placed to build variant databases.
